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In The absence of this enzyme, as in Crigler-Najjar syndrome type I, the amounts of unconjugated bilirubin will increase, leading to jaundice. Unconjugated bilirubin is water-insoluble, and high stages can deposit inside the brain leading to a condition referred to as kernicterus. Significant hyperbilirubinemia normally develops in the very first https://www.youtube.com/shorts/IuPMi7CvqAo


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